The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Differentiation between intra- and extra-hepatic cholestasis is made by clinical assessment and, as appropriate, diagnostic imaging.
Significant cholestasis may exist without jaundice being apparent.
Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Gamma glutamyltransferase (AST/ALT ratio), Lactate dehydrogenase, Bilirubin; Prothrombin time, Full blood count.
Liver biopsy, (Fine needle aspiration biopsy), if appropriate.
See under Pancreatic neoplasm.
Primary sclerosing cholangitis
Primary biliary cirrhosis
Mitochondrial Ab, Immunoglobulins G, A, M. Marked elevation of IgM is suggestive of primary biliary cirrhosis.
Helminth infection, including
Ova cysts parasites faeces. Identification of fluke found at operation.
Fasciola hepatica Ab are of value for establishing the diagnosis and for monitoring treatment.
Cholestasis of pregnancy (oestrogen related)
Liver biopsy. Porphyrins urine.
Bile acids - specialised laboratory.
Hepatocellular disease, especially
Primary hepatocellular disorders often have a cholestatic component.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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