Microangiopathic haemolytic anaemia (MAHA) is a non-immune haemolysis with prominent red cell fragmentation observed on peripheral blood film.
Full blood count, Blood film, Platelet count, Reticulocyte count; Bilirubin, Haptoglobin, Lactate dehydrogenase; Haemoglobin urine, Haemosiderin urine.
Urea, Creatinine, eGFR, LFT.
Coagulation testing, especially PT, APTT, Fibrinogen, D Dimer.
ADAMTS-13 activity assay may be indicated if Thrombotic thrombocytopenic purpura (TTP) is considered and should be collected prior to therapy if possible.
See also Disseminated intravascular coagulation, Haemolysis